vismodegib) can offer temporary relief, but are not curative because side effects typically limit the time that patients can remain on these medications 6. New hedgehog pathway inhibitory drugs (e.g. Surgical treatment of multiple BCC tumors, starting in childhood and often numbering into the hundreds over a lifetime, causes extensive scarring that can be highly debilitating both functionally and psychologically 5. Basal cell nevus syndrome (BCNS Gorlin Gorlin-Goltz) is a chronic genetic condition characterized by basal cell carcinoma (BCC) skin tumors and odontogenic jaw cysts before the age of 20 years, palmar/plantar pitting, brain calcifications, various skeletal and soft tissue abnormalities, and a high risk for developing medulloblastoma 1- 4.
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